一、简况
赵岩,博士,副教授,硕士生导师,Biosensors期刊客座编辑。2021年博士毕业于湖南大学化学化工学院,致力于纳米材料基础研究及应用研究工作。主要从事智能纳米组装体构筑、响应型生物材料设计及在生物传感、疾病诊疗中的应用研究。以主要参与人身份发表论文30余篇,其中第一及通讯作者身份发表SCI一区论文11篇,第一及通讯作者发表论文引用300次,累计影响因子>150,授权发明专利7项。主讲本科生《分析化学》、《仪器分析》、《仪器分析实验》等课程。
二、教育与工作履历
2021.10 - 今 B体育官网 B体育官网 副教授
2016.09 – 2021.06 湖南大学 化学 博士
2013.09 – 2016.06 B体育官网 分析化学 硕士
2008.09 – 2012.06 B体育官网 化学工程与工艺 学士
三、主持及参与的科研项目
国家自然科学基金委员会,青年科学基金项目,22304100,2024-01-01至2026-12-30,30万元,主持
山东省自然科学基金委员会,青年科学基金项目,ZR202111250184,2023-01-01至2025-12-30,15万元,在研,主持
山东省自然科学基金委员会,重大项目,ZR2022ZD28,2023-01-01至2025-12-30,100万元,在研,参与
国家自然科学基金委员会,重大项目,21890744,2019-01-01至2023-12-31,450万元,在研,参与
国家自然科学基金委员会,面上项目,51872088,2019-01-01至2022-12-31,60万元,结题,参与
国家自然科学基金委员会,青年科学基金项目,21705037,结题,参与
四、授权专利
(1) 荧光碳点CDs溶液、CDs-MnO2复合材料及其制备方法和应用,2018-8-10,中国专利,ZL2016103008841,渠凤丽、裴海盟、赵岩、张小宾
(2) 一种ZnO-Au@CdS光电复合材料及其制备方法和应用,2018-4-13,中国专利,ZL2016103014768,渠凤丽、赵岩、张小宾、裴海盟
(3) 一种SiO2-DNA纳米材料及其制备方法和应用,2018-3-2,中国专利,ZL2016103222629,渠凤丽、张小宾、赵岩、裴海盟、杜蕙同
(4) 一种二茂铁/氧化石墨烯/溶胶-凝胶硅膜及其制备方法和葡萄糖生物传感器,2017-6-27,中国专利,ZL2015101458986,渠凤丽、赵岩
(5) 一种空壳型聚多巴胺吸附纳米金复合材料及其制备和应用,2017-4-12,中国专利,ZL2014103943784,渠凤丽、赵岩
(6) 一种纳米金复合材料免疫传感器的制备方法及应用,2016-5-25,中国专利,ZL2015100713268,渠凤丽、赵岩
(7) 一种具有类酶活性的二维Cu-CAT纳米片及其制备方法与应用,2023-7-7,中国专利,ZL2022111258045,渠凤丽、王芳、夏莲、赵岩、孔维恒
五、一作及通讯文章
(1) Yan Zhao, Xinquan Yu, Weiheng Kong,Rong-mei Kong, Ensheng Zhang, Lian Xia, Jing Zhang, Fengli Qu* and Weihong Tan. Responsive calcium-derived nanoassemblies induce mitochondrial disorder to promote tumor calcification. Chem. Sci. 2023, 10.1039/d3sc02945j [自然指数,SCI一区,TOP期刊,IF= 8.4]
(2) Yan Zhao, Xinquan Yu, Xiao Liu, Dailiang Zhang, He Li, Hanlin Zhou, Weiheng Kong, and Fengli Qu. ClO- Induced Dual-Excitation Fluorescent Probes Responding to Diverse Testing Modes with Ratio Methodology, Analytical chemistry, 2023, DOI: 10.1021/acs.analchem.2c05532 [自然指数,SCI一区,TOP期刊,IF= 8.008]
(3) Lingdong Zhang, Xiuli Wang, Weiheng Kong, Yan Zhao*, Lian Xia*, Fengli Qu. An enhanced-stability metal–organic framework of NH2-MIL-101 as an improved fluorescent and colorimetric sensor for nitrite detection based on diazotization reaction. Sensors & Actuators: B. Chemical, 2023, 386, 133768 [SCI一区,TOP期刊,IF= 9.221]
(4) Zhao Y, Lu C, Zhao XE, Kong W, Zhu S, Qu F. A T-rich nucleic acid-enhanced electrochemical platform based on electroactive silver nanoclusters for miRNA detection. Biosensors and Bioelectronics. 2022, 15; 208, 114215 [SCI一区,TOP期刊,IF= 12.545]
(5) Zhao Y, Li X, Xiang MH, Gao F, Qu F, Li M, Lu L. Enzyme-free nucleic acid dual-amplification strategy combined with mimic enzyme catalytic precipitation reaction for the photoelectrochemical detection of microRNA-21. Microchimica Acta. 2022, 189(7), 249 [SCI一区,IF= 6.408]
(6) Yan Zhao; Weiheng Kong; Peng Wang; Guosheng Song; Zhiling Song; Yue Yang; Youjuan Wang; Baoli Yin; Pengfei Rong; Shuangyan Huan; Xiao-bing Zhang*; Tumor-specific multipath nucleic acid damages strategy by symbiosed nanozyme@enzyme with synergistic self-cyclic catalysis, Small, 2021, 17, 2100766 [SCI一区,TOP期刊,IF= 15.153]
(7) Haifeng Yuan#; Yan Zhao#; Chan Yang; Cheng Zhang; Yue Yang; Hongmin Meng; Shuangyan Huan; Guosheng Song; Xiaobing Zhang ; Copper-thioguanine metallodrug with self-reinforcing circular catalysis for activatable MRI imaging and amplifying specificity of cancer therapy, SCIENCE CHINA Chemistry, 2020, 63(7), 924-935 [SCI一区,TOP期刊,IF= 10.138]
(8) Yan Zhao, Jian Gong, Xiaobin Zhang, Rongmei Kong, Fengli Qu*, Enhanced biosensing platform constructed using urchin-like ZnO-Au@CdS microspheres based on the combination of photoelectrochemical and bioetching strategies, Sensors & Actuators B: Chemical, 2018, 255, 1753–1761 [SCI一区,TOP期刊,IF= 9.221]
(9) Yan Zhao, Ying Wang, Xiaobin Zhang, Rongmei Kong, Lian Xia, Fengli Qu*, Cascade enzymatic catalysis in poly(acrylicacid) brushes-nanospherical silica for glucose detection, Talanta, 2016, 155, 265–271 [SCI一区,TOP期刊,IF= 6.556]
(10) Yan Zhao, YiqunZheng, Rongmei Kong, Lian Xia, Fengli Qu*, Ultrasensitive electrochemical immunosensor based on horseradish peroxidase (HRP)-loaded silica-poly(acrylic acid) brushes for protein biomarker detection, Biosensors and Bioelectronics, 2016, 75, 383–388 [SCI一区,TOP期刊,IF= 12.545]
(11) Yan Zhao, Yiqun Zheng, Caiyun Zhao, Jinmao You, Fengli Qu*, Hollow PDA-Au nanoparticles-enabled signal amplification for sensitive nonenzymatic colorimetric immune detection of carbohydrate antigen125, Biosensors and Bioelectronics, 2015, 71, 200–206 [SCI一区,TOP期刊,IF= 12.545]
(12) Yan Zhao, Yaowen Yeh, Rui Liu, Jinmao You, Fengli Qu*, Facile deposition of gold nanoparticles on coreshell Fe3O4@polydopamine as recyclable nanocatalyst, Solid State Science, 2015, 45, 9-14 [SCI一区,IF= 3.752]
六、主要参与人文章
(1) Na Liang, Xinyue Ge, Yan Zhao, Lian Xia, Zhi-Ling Song, Rong-Mei Kong, Fengli Qu Promoting sensitive colorimetric detection of hydroquinone and Hg2+ via ZIF-8 dispersion enhanced oxidase-mimicking activity of MnO2 nanozyme, Journal of Hazardous Materials, 2023, 24 131455
(2) Ensheng Zhang, Xiufang Hou, Xinyu Han, Shuping Wang, He Li, Dekun Jiang, Yan Zhao, Meihao Xiang, Fengli Qu, Ping Ju*, A series of AIE dyes derived from shikimic acid: The thermo/pressure dependent fluorescence and application in the sensing of arginine, Dyes and Pigments, 2023, 210, 111041
(3) Xiankang Niu, Yan Zhao, Fang Wang, Jinghua Wu, Fengli Qu*, Weihong Tan, Ultrasensitive Photoelectrochemical Biosensor Based on Novel Z-Scheme Heterojunction of Zn–Defective CdS/ZnS for MicroRNA Assay, Analytical Chemistry, 2021, 93, 17134−17140
(4) Weiheng Kong, Linlin Wang, Yan Zhao, Hong Chen, Yunming Liu, Xiaoyan Han, Ying Yang, Juan Wang, Changjun You*, Yanlan Liu, Sequential module coordination-driven programmable function switch of metal-molecule nanoframeworks for cancer theranostics, Nano Today, 2021, 38: 101126
(5) Shi Linan, Wang Youjuan, Zhang Cheng, Zhao Yan, Lu Chang, Yin Baoli, Yang Yue, Gong Xiangyang, Teng Lili, Liu Yanlan, Zhang Xiaobing, Song Guosheng*. An acidity-unlocked magnetic nanoplatform enables self-boosting ROS generation through upregulation of lactate for imaging-guided highly specific chemodynamic therapy. Angewandte Chemie International Edition, 2021, 60: 2-13
(6) Youjuan Wang, Guosheng Song, Shiyi Liao, Qiaoqiao Qin, Yan Zhao, Linan Shi, Kesong Guan, Xiangyang Gong, Peng Wang, Xia Yin, Qian Chen, and Xiao-Bing Zhang*, Cyclic Amplification of the Afterglow Luminescent Nanoreporter Enables the Prediction of Anti-cancer Efficiency,Angewandte Chemie International Edition, 2021, 60, 19779-19789
(7) Zhang Cheng, Li Jiaqi, Lu Chang, Yang Tengxiang, Zhao Yan, Teng Lili, Yang Yue, Song Guosheng*, Zhang Xiao-Bing. H2S-activated “one-key triple-lock” bis-metal coordination network for visualizing precise therapy of colon cancer. CCS Chemistry, 2020, 2: 2126–2142
(8) Fangfang Chen, Lili Teng, Chang Lu, Cheng Zhang, Qiming Rong, Yan Zhao, Yue Yang, Youjuan Wang, Guosheng Song, and Xiao-bing Zhang*, Activatable Magnetic/Photoacoustic Nanoplatform for Redox-Unlocked Deep-tissue Molecular Imaging In Vivo via Prussian Blue Nanoprobe, Analytical Chemistry, 2020, 92, 19, 13452–13461
(9) Lu Chang, Zhang Cheng, Wang Peng, Zhao Yan, Yang Yue, Wang Youjuan, Yuan Haifeng, Qu Shuanglin, Zhang Xiaobing, Song Guosheng*, Pu Kanyi. Light-free generation of singlet oxygen through manganese-thiophene nanosystems for pH-responsive chemiluminescence imaging and tumor therapy. Chem, 2020, 6(9): 2314-2334
(10) Wang Bingzhe, Wang Youjuan, Wang Yanpei, Zhao Yan, Yang Chan, Zeng Zebing, Huan Shuangyan, Song Guosheng*, Zhang Xiaobing. Oxygen-embedded pentacene based near-infrared chemiluminescent nanoprobe for highly selective and sensitive visualization of peroxynitrite in vivo. Analytical Chemistry, 2020, 92(5): 4154-4163
(11) Yin Sheng-Yan, Song Guosheng*, Yang Yue, Zhao Yan, Wang Peng, Zhu Long-Min, Yin Xia,* Zhang Xiao-Bing.* Persistent regulation of tumor microenvironment via circulating catalysis of MnFe2O4@metal–organic frameworks for enhanced photodynamic therapy. Advanced Functional Materials, 2019, 29(25): 1901417
(12) Yin Baoli, Wang Yanpei, Zhang Cheng, Zhao Yan, Wang Youjuan, Teng Lili, Yang Yue, Zeng Zebing, Huan Shuangyan, Song Guosheng*, Zhang Xiaobing. Oxygen-embedded quinoidal acene based semiconducting chromophore nanoprobe for amplified photoacoustic imaging and photothermal therapy. Analytical Chemistry, 2019, 91(23): 15275-15283
(13) Xiong Mengyi, Rong Qiming, Kong Gezhi, Yang Chan, Zhao Yan, Qu Feng-Li*, Zhang Xiao-Bing*, Tan Weihong. Hybridization chain reaction-based nanoprobe for cancer cell recognition and amplified photodynamic therapy. Chemical Communications, 2019, 55(21): 3065-3068
(14) Yang Yue, Chen Mei*, Wang Bingzhe, Wang Peng, Liu Yongchun, Zhao Yan, Li Kun, Song Guosheng, Zhang Xiao-Bing*, Tan Weihong. NIR-II driven plasmon-enhanced catalysis for a timely supply of oxygen to overcome hypoxia-induced radiotherapy tolerance. Angewandte Chemie International Edition, 2019, 58(42): 15069-15075
(15) Rong-Mei Kong, Yan Zhao, Yiqun Zheng and Fengli Qu*, Facile synthesis of ZnO/CdS@ZIF-8 core–shell nanocomposites and their applications in photocatalytic degradation of organic dyes, RSC Advance, 2017, 7, 31365–31371
(16) Ensheng Zhang, Long Jiang, He Li, Shuping Wang, Guixue Zhang, Anzhang Li, Weiheng Kong, Yan Zhao, Meihao Xiang, Ping Ju, Fengli Qu*,The inter-molecular hydrogen bonds modulated reversible ACQ-AIE conversion and dual-states sensing applications of shikimic acid derived hydrogen bond dimers, Dyes and Pigments DOI: 10.1016/j.dyepig.2023.111616 ( IF 4.5 )
(17) Mei-Hao Xiang, Zhi-Yuan Jiang, Wen-Long Zhao, Ensheng Zhang, Lian Xia, Rong-Mei Kong, Yan Zhao, Weiheng Kong, Xianjun Liu*, Fengli Qu*, Weihong Tan, Activatable Near-Infrared Fluorescent and Photoacoustic Dual-Modal Probe for Highly Sensitive Imaging of Sulfatase In Vivo, ACS Sensors, DOI: 10.1021/acssensors.3c00201(IF 8.9)
七、联系方式
E-mail:yanzhao2016@hnu.edu.cn
办公地址:B体育官网 科技实验大楼302室
通讯地址:山东省曲阜市静轩西路57号 B体育官网 B体育官网
邮政编码:273165