教育与工作经历

2004.09-2006.07    B体育官网   学士    化学

2006.09-2011.10    湖南大学       博士    分析化学

2011.11-至今         B体育官网   教授

2006年9月-2011年10月，在湖南大学化学生物传感与计量学国家重点实验室攻读博士学位（硕博连读），师从俞汝勤院士、张晓兵教授，在博士研究后期得到了谭蔚泓教授的指导。主要从事基于功能核酸和纳米材料的生物传感器的研究及应用。已在包括Journal of the American Chemical Society、Analytical Chemistry、Small、Chemical Communications、Biosensors and Bioelectronics等权威SCI源刊物上发表国际学术论文十几篇。2011年10月获湖南大学分析化学专业理学博士学位后任职于B体育官网化学化工学院，山东省生命有机分析重点实验室。

科研项目

1. 主持国家自然科学基金青年项目1项：新型 DNAzyme 荧光纳米探针的构建及其生物医学应用研究（21205068）

2. 主持博士基金项目1项：基于银纳米簇信标构建非标记DNAzyme工具探针用于非辅助因子目标物的检测研究（BS2013SW012）

3. 主持化学生物传感与计量学国家重点实验室开放基金1项：基于DNAzyme 自组装纳米材料荧光探针的构建及初步生物医学应用研究（2013011）

获奖情况

山东软科学优秀成果奖一等奖：以生物传感技术构建疾病早期筛查机制的调查分析研究（山东软科学优秀成果奖励委员会）第二位

发表论文

[1]           Rong-Mei Kong, Xiao-Bing Zhang*, Liang-Liang Zhang, Yan Huang, Dan-Qing Lu, Weihong Tan*, Guo-Li Shen, and Ru-Qin Yu. Molecular Beacon-Based Junction Probes for Efficient Detection of Nucleic Acids via a True Target-Triggered Enzymatic Recycling Amplification. Analytical Chemistry, 2011, 83(1), 14-17.（SCI一区，IF=5.856）

[2]           Rong-Mei Kong, Xiao-Bing Zhang*, Zhuo Chen, Hong-Min Meng, Zhi-Ling Song, Weihong Tan*, Guo-Li Shen, Ru-Qin Yu. A Unimolecular Catalytic DNA Biosensor for Amplified Detection of L-Histidine via an Enzymatic Recycling Cleavage Strategy. Analytical Chemistry, 2011, 83(20), 7603-7607. （SCI一区，IF=5.856）

[3]           Rong-Mei Kong, Xiao-Bing Zhang*, Liang-Liang Zhang, Xiao-Yong Jin, Shuang-Yan Huan, Guo-Li Shen and Ru-Qin Yu*. An Ultrasensitive Electrochemical “Turn-On” Label-Free Biosensor for Hg²⁺ with AuNP-Functionalized Reporter DNA as a Signal Amplifier. Chemical Communications, 2009, 5633-5635. （SCI二区，IF=6.169）

[4]           Rong-Mei Kong, Xiao-Bing Zhang*, Zhuo Chen, Weihong Tan*. Aptamer-assembled Nanomaterials for Biosensing and Biomedical Applications. Small, 2011, 7(17), 2428-2436.（SCI二区，IF=8.349）

[5]           Rong-Mei Kong, Ting Fu, Ni-Na Sun, Feng-Li Qu, Shu-Fang Zhang, Xiao-Bing Zhang. Pyrophosphate-regulated Zn²⁺-dependent DNAzyme activity: An amplifiedfl uorescence sensing strategy for alkaline phosphatase. Biosensors and Bioelectronics, 2013, 50, 351- 355. (SCI 一区，IF=6.451)

[6]           Rong-Mei Kong, Zhi-Ling Song, Hong-Min Meng, Xiao-Bing Zhang, Guo-Li Shen, Ru-Qin Yu. A label-free electrochemical biosensor for highly sensitive and selective detection of DNA via a dual-amplified strategy. Biosensors and Bioelectronics, 2014, 54, 442- 447. (SCI 一区，IF=6.451)

[7]           Rong-Mei Kong, Zhuo Chen, Xiao-Bing Zhang*, Weihong Tan*. Cell-SELEX-based Aptamer-Conjugated Nanomaterials for Enhanced Targeting of Cancer Cells. Science in China Series B: Chemistry, 2011, 54(8), 1218-1226. （SCI 四区，IF=1.02）

[8]           Xiao-Bing Zhang*, Rong-Mei Kong, Yi Lu*. Metal Ion Sensors Based on DNAzymes and Related DNA Molecules. Annual Review of Analytical Chemistry, 2011, 4, 105-128.（SCI一区，IF=11.806）

[9]           Li-Min Lu, Xiao-Bing Zhang*, Rong-Mei Kong, Bin Yang, Weihong Tan*. A Ligation-triggered DNAzyme Cascade for Amplified Fluorescence Detection of Biological Small Molecules with Zero-Background Signal. Journal of the American Chemical Society, 2011, 133 (30), 11686-11691.（SCI一区，IF=9.907）

[10]       Xu-Hua Zhao, Rong-Mei Kong, Xiao-Bing Zhang*, Hong-Min Meng, Wei-Na Liu, Weihong Tan*, Guo-Li Shen, and Ru-Qin Yu. Graphene–DNAzyme Based Biosensor for Amplified Fluorescence “Turn-On” Detection of Pb²⁺ with a High Selectivity. Analytical Chemistry, 2011, 83(13), 5062-5066. （SCI一区，IF=5.856）

[11]       Yun-Hong Sun, Rong-Mei Kong, Dan-Qing Lu, Xiao-Bing Zhang*, Hong-Min Meng, Weihong Tan*, Guo-Li Shen and Ru-Qin Yu. A Nanoscale DNA–Au Dendrimer as a Signal Amplifier for the Universal Design of Functional DNA-Based SERS Biosensors. Chemical Communications, 2011, 47(13), 3840-3842.（SCI二区，IF=6.169）

[12]       Kejun Feng, Rongmei Kong, Hua Wang, Shufang Zhang, Fengli Qu*. A universal amplified strategy for aptasensors: Enhancing sensitivity through allostery-triggered enzymatic recycling amplification. Biosensors and Bioelectronics, 2012, 38, 121-125. （SCI一区，IF=5.602）

[13]       Rong Hu, Xiao-Bing Zhang*, Rong-Mei Kong, Xu-Hua Zhao, Jianhui Jiang*, Weihong Tan*. Nucleic Acid–Functionalized Nanomaterials for Bioimaging Applications. Journal of Materials Chemistry, 2011, 21, 16323-16334. （SCI二区，IF=5.968）

[14]       Rong Hu, Ting Fu, Xiao-Bing Zhang*, Rong-Mei Kong, Li-Ping Qiu, Ya-Ru Liu, Xiao-Tong Liang, Weihong Tan*, Guo-Li Shen, and Ru-Qin Yu. Proximity-Dependent Surface Hybridization Strategy for Constructing Efficient Signal-On Electrochemical DNAzyme Sensing System. Chemical Communications, 2012, 48, 9507-9509.（SCI二区，IF=6.169）

[15]       Rong Hu, Ya-Ru Liu, Rong-Mei Kong, Michael J. Donovan, Xiao-Bing Zhang*, Weihong Tana, Guo-Li Shen, Ru-Qin Yu*. Double-strand DNA-templated Formation of Copper Nanoparticles as Fluorescent Probe for Label Free Nuclease Enzyme Detection. Biosensors and Bioelectronics, 2013, 42, 31-35.（SCI一区，IF=6.451）

[16]       Lu Ding, Jinmao You, Rongmei Kong, Fengli Qu∗, Signal amplification strategy for sensitive immunoassay of prostatespecific antigen (PSA) based on ferrocene incorporated polystyrenespheres. Analytica Chimica Acta, 2013, 793, 19-25. (SCI二区，IF=4.718)

[17]       Ting Fu, Xu-Hua Zhao, Hua-Rong Bai, Zi-Long Zhao, Rong Hu, Rong-Mei Kong, Xiao-Bing Zhang,* Weihong Tan* and Ru-Qin Yu. A superquenched DNAzyme–perylene complex: a convenient, universal and low-background strategy for fluorescence catalytic biosensors. Chemical Communications, 2013, 49, 6644-6646. (SCI二区，IF=6.718）

[18]       Zhi-Xiang Han, Hong-Yuan Luo, Xiao-Bing Zhang*, Rong-Mei Kong, Guo-Li Shen, Ru-Qin Yu*. A Ratiometric Chemosensor for Fluorescent Determination of Hg²⁺ Based on a New Porphyrin-Quinoline Dyad. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2009, 72(5), 1084-1088. （SCI 四区，IF=1.511）

[19]       Shufang Zhang, Xuejun Sun, Fengli Qu, Rongmei Kong. Molecular spectroscopic studies on the interaction of ferulic acid with calf thymus DNA. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2013, 112, 78–83.（SCI 三区，IF=2.129）